The Interactions of Nutrition and Sleep Quality Focus on Melatonin Synthesis: A literature Review




Nutrition, Macronutrients, Micronutrients, Sleep quality, Melatonin


Aim: Nutrition plays a role as a provider of energy for the human body which is important for the formation and maintenance, especially to improve the quality of sleep seen from the production of the hormone melatonin. The purpose of this study was to determine the interaction of nutrition on sleep quality: the focus synthesis of melatonin.

Design: We performed a literature review study by reviewing 6 international journals related to the interaction of nutrition and sleep quality: focused on melatonin synthesis.

Methods: Data collection was done by searching for data-based articles or journals published through the Willey Online Library, PMC, Proquest, and Pubmed. The data were analyzed by descriptive analysis and the journals were assessed using JBI.

Results: The interaction of nutrition and sleep quality is seen from the hormone melatonin, based on the results of 6 journals. The results were described that the relationship between macronutrient and micronutrient nutrition on melatonin production that affects human sleep quality.

Conclusions: Macronutrients and micronutrients are related to sleep quality in increasing the production of the hormone melatonin.



Darnton-Hill I. Public Health Aspects in the Prevention and Control of Vitamin Deficiencies. Curr Dev Nutr. September 2019;3(9):nzz075.

Penelitian B, 2018. PKKR tahun. Riset Kesehatan Dasar (Riskesdas). Jakarta; 2018.

Fauzi CA. Analisis Pengetahuan Dan Perilaku Gizi Seimbang Menurut Pesan Ke-6, 10, 11, 12 Dari Pedoman Umum Gizi Seimbang (Pugs) Pada Remaja. Indones J Reprod Heal. 2012;3(2):91–105.

Bhaskar S, Hemavathy D, Prasad S. Prevalence of chronic insomnia in adult patients and its correlation with medical comorbidities. J Fam Med Prim care [Internet]. 2016;5(4):780–4. Tersedia pada:

McArdle N, Ward S V, Bucks RS, Maddison K, Smith A, Huang R-C, et al. The prevalence of common sleep disorders in young adults: a descriptive population-based study. Sleep. Oktober 2020;43(10).

Ho ECM, Siu AMH. Occupational therapy practice in sleep management: A review of conceptual models and research evidence. Occup Ther Int. 2018;2018:16–8.

de Ridder D, Kroese F, Evers C, Adriaanse M, Gillebaart M. Healthy diet: Health impact, prevalence, correlates, and interventions. Psychol Heal. 2017;32(8):907–41.

Lindseth G, Lindseth P, Thompson M. Nutritional Effects on Sleep. West J Nurs Res. April 2013;35(4):497–513.

Cheng W, Sekartini R. Hubungan Status Gizi, Asupan Besi, dan Magnesium dengan Gangguan Tidur Anak Usia 5-7 Tahun di Kampung Melayu, Jakarta Timur Tahun 2012. eJournal Kedokt Indones. 2014;2(2):7–12.

Pereira N, Naufel MF, Ribeiro EB, Tufik S, Hachul H. Influence of Dietary Sources of Melatonin on Sleep Quality: A Review. J Food Sci. 2020;85(1):5–13.

Hudson JL, Zhou J, Campbell WW. Adults Who Are Overweight or Obese and Consuming an Energy-Restricted Healthy US-Style Eating Pattern at Either the Recommended or a Higher Protein Quantity Perceive a Shift from “Poor” to “Good” Sleep: A Randomized Controlled Trial. J Nutr. Desember 2020;150(12):3216–23.

Wu W, Zhao A, Szeto IM-Y, Wang Y, Meng L, Li T, et al. Diet quality, consumption of seafood and eggs are associated with sleep quality among Chinese urban adults: A cross-sectional study in eight cities of China. Food Sci Nutr. Juni 2019;7(6):2091–102.

Yang T-H, Chen YC, Ou T-H, Chien Y-W. Dietary supplement of tomato can accelerate urinary aMT6s level and improve sleep quality in obese postmenopausal women. Clin Nutr. Januari 2020;39(1):291–7.

Panurywanti E, Wiboworini B, Indarto D. The effect of banana dose and duration on the decrease of sleep disorders in the elderly. J Med Allied Sci. 2021;11(1):71.

Tavakoli A, Mirzababaei A, Mirzaei K. Association between low carbohydrate diet (LCD) and sleep quality by mediating role of inflammatory factors in women with overweight and obesity: A cross-sectional study. Food Sci Nutr. 2021;(April):6252–61.

Bazyar H, Zare Javid A, Dasi E, Sadeghian M. Major dietary patterns in relation to obesity and quality of sleep among female university students. Clin Nutr ESPEN. 2020;39(xxxx):157–64.

Additional Files



How to Cite

Mashfufa, E. W., Sari, R. K., Marina, N. S. A. P., Aini, N., Setyowati, L. ., & Marta, O. F. D. (2022). The Interactions of Nutrition and Sleep Quality Focus on Melatonin Synthesis: A literature Review . Jurnal Keperawatan Komprehensif (Comprehensive Nursing Journal), 8(2).